Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism

AIMS/HYPOTHESIS: Diabetes interferes with bone formation and impairs fracture healing, an important complication in humans and animal models. The aim of this study was to examine the impact of diabetes on mesenchymal stem cells (MSCs) during fracture repair. METHODS: Fracture of the long bones was i...

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Pubblicato in:Diabetologia
Autori principali: Ko, Kang I., Coimbra, Leila S., Tian, Chen, Alblowi, Jazia, Kayal, Rayyan A., Einhorn, Thomas A., Gerstenfeld, Louis C., Pignolo, Robert J., Graves, Dana T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346353/
https://ncbi.nlm.nih.gov/pubmed/25563724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3470-y
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