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Chimeric Mouse Model for MRI Contrast Agent Evaluation
PURPOSE: While rodents are the primary animal models for contrast agent evaluation, rodents can potentially misrepresent human organ clearance of newly developed contrast agents. For example, Gd-BOPTA has ~50% hepatic clearance in rodents, but ~5% in humans. This study demonstrates the benefit of ch...
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| 出版年: | Magn Reson Med |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491262/ https://ncbi.nlm.nih.gov/pubmed/30874333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.27730 |
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