Dynamic Contrast–Enhanced MRI of OATP Dysfunction in Diabetes

Diabetes is associated with hepatic metabolic dysfunction predisposing patients to drug-induced liver injury. Mouse models of type 2 diabetes (T2D) have dramatically reduced expression of organic anion transporting polypeptide (OATP)1A1, a transporter expressed in hepatocytes and in the kidneys. The...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Shuboni-Mulligan, Dorela D., Parys, Maciej, Blanco-Fernandez, Barbara, Mallett, Christiane L., Schnegelberger, Regina, Takada, Marilia, Chakravarty, Shatadru, Hagenbuch, Bruno, Shapiro, Erik M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Technological Advances
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341305/
https://ncbi.nlm.nih.gov/pubmed/30487262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0525
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