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A Kv1.3 channel‐specific blocker alleviates neurological impairment through inhibiting T‐cell activation in experimental autoimmune encephalomyelitis

AIM: Multiple sclerosis (MS) is a neurological autoimmune disorder characterized by mistaken attacks of inflammatory cells against the central nervous system (CNS), resulting in demyelination and axonal damage. Kv1.3 channel blockers can inhibit T‐cell activation and have been designed for MS therap...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Yuan, Xiao‐Lu, Zhao, Yi‐Peng, Huang, Jie, Liu, Jun‐Chen, Mao, Wen‐Qian, Yin, Jun, Peng, Bi‐Wen, Liu, Wan‐Hong, Han, Song, He, Xiao‐Hua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490025/
https://ncbi.nlm.nih.gov/pubmed/29577640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12848
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