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Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1‐G93A mouse model
AIMS: To investigate the effect and mechanisms of carbamazepine (CBZ) on the onset and progression of amyotrophic lateral sclerosis (ALS) in SOD1‐G93A mouse model. METHODS: Starting from 64 days of age, SOD1‐G93A mice were orally administered with CBZ at 200 mg/kg once daily until death. The disease...
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| Publicado en: | CNS Neurosci Ther |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6489874/ https://ncbi.nlm.nih.gov/pubmed/29656576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12855 |
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