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Increased Orexin Expression Promotes Sleep/Wake Disturbances in the SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis
BACKGROUND: Sleep/wake disturbances in patients with amyotrophic lateral sclerosis (ALS) are well-documented, however, no animal or mechanistic studies on these disturbances exist. Orexin is a crucial neurotransmitter in promoting wakefulness in sleep/wake regulation, and may play an important role...
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| Опубликовано в: : | Chin Med J (Engl) |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Medknow Publications & Media Pvt Ltd
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837845/ https://ncbi.nlm.nih.gov/pubmed/25591569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.149214 |
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