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Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1‐G93A mouse model

AIMS: To investigate the effect and mechanisms of carbamazepine (CBZ) on the onset and progression of amyotrophic lateral sclerosis (ALS) in SOD1‐G93A mouse model. METHODS: Starting from 64 days of age, SOD1‐G93A mice were orally administered with CBZ at 200 mg/kg once daily until death. The disease...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:CNS Neurosci Ther
Päätekijät: Zhang, Jing‐Jing, Zhou, Qin‐Ming, Chen, Sheng, Le, Wei‐Dong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489874/
https://ncbi.nlm.nih.gov/pubmed/29656576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12855
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