Tetramethylpyrazine attenuated bupivacaine-induced neurotoxicity in SH-SY5Y cells through regulating apoptosis, autophagy and oxidative damage

Background: Bupivacaine (BUP) acts as a local anesthetic, which is extensively used for clinical patients but could generate neurotoxicity in neurons. Tetramethylpyrazine (TET) exhibits strong neuron protective effects against neurotoxicity. Hence, we investigate the effect of TET on BUP-induced neu...

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Detaylı Bibliyografya
Yayımlandı:Drug Des Devel Ther
Asıl Yazarlar: Wang, Shouliang, Xia, Bin, Qiao, Zonglei, Duan, Lian, Wang, Gongming, Meng, Wenjun, Liu, Zhifei, Wang, Yu, Zhang, Mengyuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489565/
https://ncbi.nlm.nih.gov/pubmed/31114159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S196172
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