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Cobalt Catalyzed Reductive Dimethylcyclopropanation of 1,3-Dienes

Dimethylcyclopropanes are valuable synthetic targets that are challenging to access in high yield using Zn carbenoid reagents. Here, we describe a cobalt-catalyzed variant of the Simmons–Smith reaction that enables the efficient dimethylcyclopropanation of 1,3-dienes using a Me(2)CCl(2)/Zn reagent m...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Werth, Jacob, Uyeda, Christopher
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489504/
https://ncbi.nlm.nih.gov/pubmed/30144253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201807542
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