Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

BACKGROUND: Genome-wide association studies (GWAS) of diseases and traits have found associations to gene regions but not the functional SNP or the gene mediating the effect. Difference in gene regulatory signals can be detected using chromatin immunoprecipitation and next-gen sequencing (ChIP-seq)...

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Bibliografiska uppgifter
I publikationen:Hum Genomics
Huvudupphovsmän: Cavalli, Marco, Baltzer, Nicholas, Pan, Gang, Bárcenas Walls, José Ramón, Smolinska Garbulowska, Karolina, Kumar, Chanchal, Skrtic, Stanko, Komorowski, Jan, Wadelius, Claes
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Primary Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489362/
https://ncbi.nlm.nih.gov/pubmed/31036066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0204-8
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