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Functional annotation of noncoding mutations in cancer

In a cancer genome, the noncoding sequence contains the vast majority of somatic mutations. While very few are expected to be cancer drivers, those affecting regulatory elements have the potential to have downstream effects on gene regulation that may contribute to cancer progression. To prioritize...

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Vydáno v:Life Sci Alliance
Hlavní autoři: Umer, Husen M, Smolinska, Karolina, Komorowski, Jan, Wadelius, Claes
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321657/
https://ncbi.nlm.nih.gov/pubmed/34282050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900523
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