Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

BACKGROUND: Genome-wide association studies (GWAS) of diseases and traits have found associations to gene regions but not the functional SNP or the gene mediating the effect. Difference in gene regulatory signals can be detected using chromatin immunoprecipitation and next-gen sequencing (ChIP-seq)...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Cavalli, Marco, Baltzer, Nicholas, Pan, Gang, Bárcenas Walls, José Ramón, Smolinska Garbulowska, Karolina, Kumar, Chanchal, Skrtic, Stanko, Komorowski, Jan, Wadelius, Claes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489362/
https://ncbi.nlm.nih.gov/pubmed/31036066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0204-8
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