Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

BACKGROUND: Genome-wide association studies (GWAS) of diseases and traits have found associations to gene regions but not the functional SNP or the gene mediating the effect. Difference in gene regulatory signals can be detected using chromatin immunoprecipitation and next-gen sequencing (ChIP-seq)...

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Détails bibliographiques
Publié dans:Hum Genomics
Auteurs principaux: Cavalli, Marco, Baltzer, Nicholas, Pan, Gang, Bárcenas Walls, José Ramón, Smolinska Garbulowska, Karolina, Kumar, Chanchal, Skrtic, Stanko, Komorowski, Jan, Wadelius, Claes
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Primary Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489362/
https://ncbi.nlm.nih.gov/pubmed/31036066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0204-8
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