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STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models
Pancreatic cancer is characterized by an immune suppressive stromal reaction that creates a barrier to therapy. A murine transgenic pancreatic cancer cell line that recapitulates human disease was used to test whether a STimulator of Interferon Genes (STING) agonist could reignite immunologically in...
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| Publicado en: | J Immunother Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6489306/ https://ncbi.nlm.nih.gov/pubmed/31036082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0573-5 |
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