Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

BACKGROUND: Patient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models using organoids in co-culture...

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Bibliografische gegevens
Gepubliceerd in:BMC Cancer
Hoofdauteurs: Tsai, Susan, McOlash, Laura, Palen, Katie, Johnson, Bryon, Duris, Christine, Yang, Qiuhui, Dwinell, Michael B., Hunt, Bryan, Evans, Douglas B., Gershan, Jill, James, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870823/
https://ncbi.nlm.nih.gov/pubmed/29587663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4238-4
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