Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

BACKGROUND: Patient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models using organoids in co-culture...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Tsai, Susan, McOlash, Laura, Palen, Katie, Johnson, Bryon, Duris, Christine, Yang, Qiuhui, Dwinell, Michael B., Hunt, Bryan, Evans, Douglas B., Gershan, Jill, James, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870823/
https://ncbi.nlm.nih.gov/pubmed/29587663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4238-4
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