NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism

NADPH donates high energy electrons for antioxidant defense and reductive biosynthesis. Cytosolic NADP is recycled to NADPH by the oxidative pentose phosphate pathway (oxPPP), malic enzyme 1 (ME1) and isocitrate dehydrogenase 1 (IDH1). Here we show that any one of these routes can support cell growt...

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Detaylı Bibliyografya
Yayımlandı:Nat Metab
Asıl Yazarlar: Chen, Li, Zhang, Zhaoyue, Hoshino, Atsushi, Zheng, Henry D., Morley, Michael, Arany, Zoltan, Rabinowitz, Joshua D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489125/
https://ncbi.nlm.nih.gov/pubmed/31058257
Etiketler: Etiketle
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