Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective

The adult myocardium relies on oxidative metabolism. In ischemic myocardium, such as the embryonic heart, glycolysis contributes more prominently as a fuel source. The sulfonylurea receptor 2 (SUR2) was previously implicated in the normal myocardial transition from glycolytic to oxidative metabolism...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Aubert, Gregory, Barefield, David Y., Demonbreun, Alexis R., Ramratnam, Mohun, Fallon, Katherine S., Warner, James L., Rossi, Ann E., Hadhazy, Michele, Makielski, Jonathan C., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488756/
https://ncbi.nlm.nih.gov/pubmed/31061927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.11.012
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