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Dynamin 2 the rescue for centronuclear myopathy

Centronuclear myopathy is a lethal muscle disease. The most severe form of the disease, X-linked centronuclear myopathy, is due to mutations in the gene encoding myotubularin (MTM1), while mutations in dynamin 2 (DNM2) and amphiphysin 2/BIN1 (AMPH2) cause milder forms of myopathy. MTM1 is a lipid ph...

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Detalhes bibliográficos
Main Authors: Demonbreun, Alexis R., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938257/
https://ncbi.nlm.nih.gov/pubmed/24569368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74434
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