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Dynamin 2 Mutants Linked to Centronuclear Myopathies Form Abnormally Stable Polymers
Mutations in the dynamin 2 gene have been identified in patients with autosomal dominant forms of centronuclear myopathy (CNM). Dynamin 2 is a ubiquitously expressed ∼100-kDa GTPase that assembles around the necks of vesiculating membranes and promotes their constriction and scission. It has also be...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906265/ https://ncbi.nlm.nih.gov/pubmed/20529869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.130013 |
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