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Dynamin 2 Mutants Linked to Centronuclear Myopathies Form Abnormally Stable Polymers

Mutations in the dynamin 2 gene have been identified in patients with autosomal dominant forms of centronuclear myopathy (CNM). Dynamin 2 is a ubiquitously expressed ∼100-kDa GTPase that assembles around the necks of vesiculating membranes and promotes their constriction and scission. It has also be...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Lei, Barylko, Barbara, Byers, Christopher, Ross, Justin A., Jameson, David M., Albanesi, Joseph P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906265/
https://ncbi.nlm.nih.gov/pubmed/20529869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.130013
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