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Eomes transcription factor is required for the development and differentiation of invariant NKT cells
Eomes regulates the differentiation of CD8(+) T cells into effector and memory phases. However, its role in invariant (i)NKT cells remains unknown. Here, we show the impact of Eomes on iNKT cells in the thymus and peripheral tissue using conditional knockout (Eomes-cKO) mice. In the thymus, CD1d-tet...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488575/ https://ncbi.nlm.nih.gov/pubmed/31044175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0389-3 |
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