Transfer of mRNA Encoding Invariant NKT Cell Receptors Imparts Glycolipid Specific Responses to T Cells and γδT Cells

Cell-based therapies using genetically engineered lymphocytes expressing antigen-specific T cell receptors (TCRs) hold promise for the treatment of several types of cancers. Almost all studies using this modality have focused on transfer of TCR from CD8 cytotoxic T lymphocytes (CTLs). The transfer o...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Shimizu, Kanako, Shinga, Jun, Yamasaki, Satoru, Kawamura, Masami, Dörrie, Jan, Schaft, Niels, Sato, Yusuke, Iyoda, Tomonori, Fujii, Shin-ichiro
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488262/
https://ncbi.nlm.nih.gov/pubmed/26121617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131477
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