Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Uridylate insertion/deletion RNA editing in Trypanosoma brucei is a complex system that is not found in humans, so there is interest in targeting this system for drug development. This system uses hundreds of small non-coding guide RNAs (gRNAs) to modify the mitochondrial mRNA transcriptome. This pr...

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Vydáno v:PLoS One
Hlavní autoři: Kumar, Vikas, Doharey, Pawan K., Gulati, Shelly, Meehan, Joshua, Martinez, Mary G., Hughes, Karrisa, Mooers, Blaine H. M., Cruz-Reyes, Jorge
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488192/
https://ncbi.nlm.nih.gov/pubmed/31034523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211525
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