Site-specific and substrate-specific control of accurate mRNA editing by a helicase complex in trypanosomes

Trypanosome U-insertion/deletion RNA editing in mitochondrial mRNAs involves guide RNAs (gRNAs) and the auxiliary RNA editing substrate binding complex (RESC) and RNA editing helicase 2 complex (REH2C). RESC and REH2C stably copurify with editing mRNAs but the functional interplay between these comp...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Kumar, Vikas, Ivens, Alasdair, Goodall, Zachary, Meehan, Joshua, Doharey, Pawan Kumar, Hillhouse, Andrew, Hurtado, Daniel Osorio, Cai, James J., Zhang, Xiuren, Schnaufer, Achim, Cruz-Reyes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668249/
https://ncbi.nlm.nih.gov/pubmed/32873716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076513.120
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