REH2C Helicase and GRBC Subcomplexes May Base Pair through mRNA and Small Guide RNA in Kinetoplastid Editosomes

Mitochondrial mRNAs in Trypanosoma brucei undergo extensive insertion and deletion of uridylates that are catalyzed by the RNA editing core complex (RECC) and directed by hundreds of small guide RNAs (gRNAs) that base pair with mRNA. RECC is largely RNA-free, and accessory mitochondrial RNA-binding...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kumar, Vikas, Madina, Bhaskara R., Gulati, Shelly, Vashisht, Ajay A., Kanyumbu, Chiedza, Pieters, Brittany, Shakir, Afzal, Wohlschlegel, James A., Read, Laurie K., Mooers, Blaine H. M., Cruz-Reyes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786712/
https://ncbi.nlm.nih.gov/pubmed/26769962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.708164
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