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Native Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing

Adaptation and survival of Trypanosoma brucei requires editing of mitochondrial mRNA by uridylate (U) insertion and deletion. Hundreds of small guide RNAs (gRNAs) direct the mRNA editing at over 3,000 sites. RNA editing is controlled during the life cycle but the regulation of substrate and stage sp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Madina, Bhaskara R., Kumar, Vikas, Mooers, Blaine H. M., Cruz-Reyes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415780/
https://ncbi.nlm.nih.gov/pubmed/25928631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123441
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