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Predicting synthetic lethal interactions using conserved patterns in protein interaction networks
In response to a need for improved treatments, a number of promising novel targeted cancer therapies are being developed that exploit human synthetic lethal interactions. This is facilitating personalised medicine strategies in cancers where specific tumour suppressors have become inactivated. Mainl...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488098/ https://ncbi.nlm.nih.gov/pubmed/30995217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006888 |
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