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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

Synthetic lethal genetic interaction networks define genes that work together to control essential functions and have been studied extensively in Saccharomyces cerevisiae using the synthetic genetic array (SGA) analysis technique (ScSGA). The extent to which synthetic lethal or other genetic interac...

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Autori principali: Dixon, Scott J., Fedyshyn, Yaroslav, Koh, Judice L. Y., Prasad, T. S. Keshava, Chahwan, Charly, Chua, Gordon, Toufighi, Kiana, Baryshnikova, Anastasija, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Myers, Chad L., Pandey, Akhilesh, Durocher, Daniel, Andrews, Brenda J., Boone, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575475/
https://ncbi.nlm.nih.gov/pubmed/18931302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806261105
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