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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

Synthetic lethal genetic interaction networks define genes that work together to control essential functions and have been studied extensively in Saccharomyces cerevisiae using the synthetic genetic array (SGA) analysis technique (ScSGA). The extent to which synthetic lethal or other genetic interac...

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Autors principals: Dixon, Scott J., Fedyshyn, Yaroslav, Koh, Judice L. Y., Prasad, T. S. Keshava, Chahwan, Charly, Chua, Gordon, Toufighi, Kiana, Baryshnikova, Anastasija, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Myers, Chad L., Pandey, Akhilesh, Durocher, Daniel, Andrews, Brenda J., Boone, Charles
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575475/
https://ncbi.nlm.nih.gov/pubmed/18931302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806261105
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