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Analysis of the dominant mutation N188T of human connexin46 (hCx46) using concatenation and molecular dynamics simulation
Connexins (Cx) are proteins that form cell‐to‐cell gap junction channels. A mutation at position 188 in the second extracellular loop (E2) domain of hCx46 has been linked to an autosomal dominant zonular pulverulent cataract. As it is dominantly inherited, it is possible that the mutant variant affe...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487695/ https://ncbi.nlm.nih.gov/pubmed/31034164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12624 |
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