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Analysis of the dominant mutation N188T of human connexin46 (hCx46) using concatenation and molecular dynamics simulation
Connexins (Cx) are proteins that form cell‐to‐cell gap junction channels. A mutation at position 188 in the second extracellular loop (E2) domain of hCx46 has been linked to an autosomal dominant zonular pulverulent cataract. As it is dominantly inherited, it is possible that the mutant variant affe...
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| Publicado en: | FEBS Open Bio |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487695/ https://ncbi.nlm.nih.gov/pubmed/31034164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12624 |
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