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Concatenation of Human Connexin26 (hCx26) and Human Connexin46 (hCx46) for the Analysis of Heteromeric Gap Junction Hemichannels and Heterotypic Gap Junction Channels

Gap junction channels and hemichannels formed by concatenated connexins were analyzed. Monomeric (hCx26, hCx46), homodimeric (hCx46-hCx46, hCx26-hCx26), and heterodimeric (hCx26-hCx46, hCx46-hCx26) constructs, coupled to GFP, were expressed in HeLa cells. Confocal microscopy showed that the tandems...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Schadzek, Patrik, Hermes, Doris, Stahl, Yannick, Dilger, Nadine, Ngezahayo, Anaclet
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163895/
https://ncbi.nlm.nih.gov/pubmed/30217016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092742
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