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Connexin 46 (Cx46) Gap Junctions Provide a Pathway for the Delivery of Glutathione to the Lens Nucleus

Maintenance of adequate levels of glutathione (GSH) in the lens nucleus is critical for protection of lens proteins from the effects of oxidative stress and for lens transparency. How GSH is transported to the nucleus is unknown. We show that GSH diffuses to the nucleus from the outer cortex, where...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Slavi, Nefeli, Rubinos, Clio, Li, Leping, Sellitto, Caterina, White, Thomas W., Mathias, Richard, Srinivas, Miduturu
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239621/
https://ncbi.nlm.nih.gov/pubmed/25294879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597898
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