Connexin 46 (Cx46) Gap Junctions Provide a Pathway for the Delivery of Glutathione to the Lens Nucleus

Maintenance of adequate levels of glutathione (GSH) in the lens nucleus is critical for protection of lens proteins from the effects of oxidative stress and for lens transparency. How GSH is transported to the nucleus is unknown. We show that GSH diffuses to the nucleus from the outer cortex, where...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Slavi, Nefeli, Rubinos, Clio, Li, Leping, Sellitto, Caterina, White, Thomas W., Mathias, Richard, Srinivas, Miduturu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Molecular Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239621/
https://ncbi.nlm.nih.gov/pubmed/25294879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597898
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