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Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity

TRIM E3 ubiquitin ligases regulate multiple cellular processes, and their dysfunction is linked to disease. They are characterised by a conserved N-terminal tripartite motif comprising a RING, B-box domains, and a coiled-coil region, with C-terminal domains often mediating substrate recruitment. TRI...

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Veröffentlicht in:Life Sci Alliance
Hauptverfasser: Stevens, Rebecca V, Esposito, Diego, Rittinger, Katrin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Life Science Alliance LLC 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487577/
https://ncbi.nlm.nih.gov/pubmed/31028095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900295
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