The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins

NOD-like receptors represent an important class of germline-encoded pattern recognition receptors that play key roles in the regulation of inflammatory signalling pathways. They function as danger sensors and initiate inflammatory responses and the production of cytokines. Since NLR malfunction resu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Martino, Luigi, Holland, Louise, Christodoulou, Evangelos, Kunzelmann, Simone, Esposito, Diego, Rittinger, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058472/
https://ncbi.nlm.nih.gov/pubmed/27727326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164662
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