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Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis
Membrane proteins are prone to misfolding and degradation within the cell, yet the nature of the conformational defects involved in this process remain poorly understood. The earliest stages of membrane protein folding are mediated by the Sec61 translocon, a molecular machine that facilitates the la...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487503/ https://ncbi.nlm.nih.gov/pubmed/30537820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08243 |
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