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Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis
Membrane proteins are prone to misfolding and degradation within the cell, yet the nature of the conformational defects involved in this process remain poorly understood. The earliest stages of membrane protein folding are mediated by the Sec61 translocon, a molecular machine that facilitates the la...
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| Vydáno v: | J Am Chem Soc |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487503/ https://ncbi.nlm.nih.gov/pubmed/30537820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08243 |
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