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COUPLING OF THE POLYAMINE AND IRON METABOLISM PATHWAYS IN THE REGULATION OF PROLIFERATION: MECHANISTIC LINKS TO ALTERATIONS IN KEY POLYAMINE BIOSYNTHETIC AND CATABOLIC ENZYMES

Many biological processes result from the coupling of metabolic pathways. Considering this, proliferation depends on adequate iron and polyamines, and although iron-depletion impairs proliferation, the metabolic link between iron and polyamine metabolism has never been thoroughly investigated. This...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta Mol Basis Dis
Auteurs principaux: Lane, Darius J. R., Bae, Dong-Hun, Siafakas, Aritee R., Rahmanto, Yohan Suryo, Al-Akra, Lina, Jansson, Patric J., Casero, Robert A., Richardson, Des R.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487307/
https://ncbi.nlm.nih.gov/pubmed/29777905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.05.007
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