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COUPLING OF THE POLYAMINE AND IRON METABOLISM PATHWAYS IN THE REGULATION OF PROLIFERATION: MECHANISTIC LINKS TO ALTERATIONS IN KEY POLYAMINE BIOSYNTHETIC AND CATABOLIC ENZYMES

Many biological processes result from the coupling of metabolic pathways. Considering this, proliferation depends on adequate iron and polyamines, and although iron-depletion impairs proliferation, the metabolic link between iron and polyamine metabolism has never been thoroughly investigated. This...

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書誌詳細
出版年:Biochim Biophys Acta Mol Basis Dis
主要な著者: Lane, Darius J. R., Bae, Dong-Hun, Siafakas, Aritee R., Rahmanto, Yohan Suryo, Al-Akra, Lina, Jansson, Patric J., Casero, Robert A., Richardson, Des R.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487307/
https://ncbi.nlm.nih.gov/pubmed/29777905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.05.007
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