COUPLING OF THE POLYAMINE AND IRON METABOLISM PATHWAYS IN THE REGULATION OF PROLIFERATION: MECHANISTIC LINKS TO ALTERATIONS IN KEY POLYAMINE BIOSYNTHETIC AND CATABOLIC ENZYMES

Many biological processes result from the coupling of metabolic pathways. Considering this, proliferation depends on adequate iron and polyamines, and although iron-depletion impairs proliferation, the metabolic link between iron and polyamine metabolism has never been thoroughly investigated. This...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta Mol Basis Dis
Main Authors: Lane, Darius J. R., Bae, Dong-Hun, Siafakas, Aritee R., Rahmanto, Yohan Suryo, Al-Akra, Lina, Jansson, Patric J., Casero, Robert A., Richardson, Des R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487307/
https://ncbi.nlm.nih.gov/pubmed/29777905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.05.007
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