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A tough row to hoe: when replication forks encounter DNA damage

Eukaryotic cells continuously experience DNA damage that can perturb key molecular processes like DNA replication. DNA replication forks that encounter DNA lesions typically slow and may stall, which can lead to highly detrimental fork collapse if appropriate protective measures are not executed. St...

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Bibliografiske detaljer
Udgivet i:Biochem Soc Trans
Main Authors: Patel, Darshil R., Weiss, Robert S.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487187/
https://ncbi.nlm.nih.gov/pubmed/30514768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20180308
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