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The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

Werner syndrome is an autosomal recessive genetic instability and cancer predisposition syndrome with features of premature aging. Several lines of evidence have suggested that the Werner syndrome protein WRN plays a role in DNA replication and S-phase progression. In order to define the exact role...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Sidorova, Julia M., Li, Nianzhen, Folch, Albert, Monnat, Raymond J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362724/
https://ncbi.nlm.nih.gov/pubmed/18250621
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