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Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy
G-quadruplexes (GQs) can adopt diverse structures and are functionally implicated in transcription, replication, translation, and maintenance of telomere. Their conformational diversity under physiological levels of mechanical stress, however, is poorly understood. We used single-molecule fluorescen...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486787/ https://ncbi.nlm.nih.gov/pubmed/30944218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815162116 |
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