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Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy
G-quadruplexes (GQs) can adopt diverse structures and are functionally implicated in transcription, replication, translation, and maintenance of telomere. Their conformational diversity under physiological levels of mechanical stress, however, is poorly understood. We used single-molecule fluorescen...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486787/ https://ncbi.nlm.nih.gov/pubmed/30944218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815162116 |
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