Loading...

Locus coeruleus toggles reciprocal prefrontal firing to reinstate fear

The medial prefrontal cortex (mPFC) plays an essential role in regulating emotion, including inhibiting fear when danger has passed. The extinction of fear, however, is labile and a number of factors, including stress, cause extinguished fear to relapse. Here we show that fear relapse in rats limits...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Giustino, Thomas F., Fitzgerald, Paul J., Ressler, Reed L., Maren, Stephen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486780/
https://ncbi.nlm.nih.gov/pubmed/30971490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814278116
Tags: Add Tag
No Tags, Be the first to tag this record!