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Noradrenergic blockade stabilizes prefrontal activity and enables fear extinction under stress
Stress-induced impairments in extinction learning are believed to sustain posttraumatic stress disorder (PTSD). Noradrenergic signaling may contribute to extinction impairments by modulating medial prefrontal cortex (mPFC) circuits involved in fear regulation. Here we demonstrate that aversive fear...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507202/ https://ncbi.nlm.nih.gov/pubmed/26124100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500682112 |
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