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Genome-wide effects on Escherichia coli transcription from ppGpp binding to its two sites on RNA polymerase
The second messenger nucleotide ppGpp dramatically alters gene expression in bacteria to adjust cellular metabolism to nutrient availability. ppGpp binds to two sites on RNA polymerase (RNAP) in Escherichia coli, but it has also been reported to bind to many other proteins. To determine the role of...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486775/ https://ncbi.nlm.nih.gov/pubmed/30971496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819682116 |
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