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Genome-wide effects on Escherichia coli transcription from ppGpp binding to its two sites on RNA polymerase

The second messenger nucleotide ppGpp dramatically alters gene expression in bacteria to adjust cellular metabolism to nutrient availability. ppGpp binds to two sites on RNA polymerase (RNAP) in Escherichia coli, but it has also been reported to bind to many other proteins. To determine the role of...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Sanchez-Vazquez, Patricia, Dewey, Colin N., Kitten, Nicole, Ross, Wilma, Gourse, Richard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486775/
https://ncbi.nlm.nih.gov/pubmed/30971496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819682116
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