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The Magic Spot: A ppGpp Binding Site on E. coli RNA Polymerase Responsible for Regulation of Transcription Initiation
The global regulatory nucleotide ppGpp (“magic spot”) regulates transcription from a large subset of Escherichia coli promoters, illustrating how small molecules can control gene expression promoter-specifically by interacting with RNA polymerase (RNAP) without binding to DNA. However, ppGpp’s targe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654024/ https://ncbi.nlm.nih.gov/pubmed/23623682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.021 |
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