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Still looking for the magic spot: the crystallographically-defined binding site for ppGpp on RNA polymerase is unlikely to be responsible for rRNA transcription regulation
Identification of the RNA polymerase (RNAP) binding site for ppGpp, a central regulator of bacterial transcription, is crucial for understanding its mechanism of action. A recent high resolution x-ray structure defined a ppGpp binding site on T. thermophilus RNAP. We report here effects of ppGpp on...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2317782/ https://ncbi.nlm.nih.gov/pubmed/18272182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.042 |
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