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Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity

The cell’s dense 3D actin filament network presents numerous challenges to vesicular transport by teams of myosin Va (MyoVa) molecular motors. These teams must navigate their cargo through diverse actin structures ranging from Arp2/3-branched lamellipodial networks to the dense, unbranched cortical...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Lombardo, Andrew T., Nelson, Shane R., Kennedy, Guy G., Trybus, Kathleen M., Walcott, Sam, Warshaw, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486769/
https://ncbi.nlm.nih.gov/pubmed/30967504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901176116
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