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Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity

The cell’s dense 3D actin filament network presents numerous challenges to vesicular transport by teams of myosin Va (MyoVa) molecular motors. These teams must navigate their cargo through diverse actin structures ranging from Arp2/3-branched lamellipodial networks to the dense, unbranched cortical...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lombardo, Andrew T., Nelson, Shane R., Kennedy, Guy G., Trybus, Kathleen M., Walcott, Sam, Warshaw, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486769/
https://ncbi.nlm.nih.gov/pubmed/30967504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901176116
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