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Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity

The cell’s dense 3D actin filament network presents numerous challenges to vesicular transport by teams of myosin Va (MyoVa) molecular motors. These teams must navigate their cargo through diverse actin structures ranging from Arp2/3-branched lamellipodial networks to the dense, unbranched cortical...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lombardo, Andrew T., Nelson, Shane R., Kennedy, Guy G., Trybus, Kathleen M., Walcott, Sam, Warshaw, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486769/
https://ncbi.nlm.nih.gov/pubmed/30967504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901176116
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