Ebolavirus polymerase uses an unconventional genome replication mechanism

Most nonsegmented negative strand (NNS) RNA virus genomes have complementary 3′ and 5′ terminal nucleotides because the promoters at the 3′ ends of the genomes and antigenomes are almost identical to each other. However, according to published sequences, both ends of ebolavirus genomes show a high d...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Deflubé, Laure R., Cressey, Tessa N., Hume, Adam J., Olejnik, Judith, Haddock, Elaine, Feldmann, Friederike, Ebihara, Hideki, Fearns, Rachel, Mühlberger, Elke
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486738/
https://ncbi.nlm.nih.gov/pubmed/30962389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815745116
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